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院長

吳明忠(Ming-Jung Wu)教授  

        服務單位:國立中山大學化學系

        辦公室電話: 07-5252000-3500

        研究室電話: 07-5252000-3914

        研究專長: 過渡金屬催化之有機反應、設計與合成新的抗癌藥物、

                          天然物之全合成研究

        e-mailmijuwu@faculty.nsysu.edu.tw 

       化學系網頁http://chem.nsysu.edu.tw/

    最高學歷

● 美國Clemson大學化學博士(1987)

    經歷

● 中山大學化學系教授 (2008-迄今)

國立中山大學化學系系主任三年(2011-2013)

高雄醫學大學醫藥暨應用化學系教授 (1994 -2008)

● 高雄醫學大學學生事務處學務長 (2000 -2006)

● 高雄醫學大學學生事務處生涯規劃暨就業輔導組組長 (1994-2000)

● 高雄醫學大學醫藥暨應用化學系副教授 (1990 - 1994)

● SmithKline Beechem Pharmaceuticals博士後研究員 (1989 - 1990)

● The Pennsylvania State University 博士後研究員 (1987 - 1989)

國科會自然處化學學門審議和諮議委員三年

科技部生物司藥學學門複審委員三年

國科會化學推動中心委員三年

國科會貴儀中心委員前後四年

高等教育評鑑委員三年

中國化學會高雄分會理監事五年

      研究方向及重點

● 過渡金屬催化之有機反應

● 設計與合成新的抗癌藥物

天然物之全合成研究

    國際交流經歷

Asian Core Program Lectureship Award, Thailand (2017)

Asian Core Program Lectureship Award, Malaysia (2015)
Asian Core Program Lectureship Award, China (2014)
Asian Core Program Lectureship Award, Korea (2012)
Asian Core Program Lectureship Award, Singapore (2010)
Asian Core Program Lectureship Award, Japan (2008)
    獎勵與榮譽
●2016年獲頒國立中山大學105學年度全校優良導師
●2014年獲頒國立中山大學103學年度理學院教學績優教師
●2011年獲頒國立中山大學100學年度學術研究績優獎 

2004年高雄醫學大學教學優良教師

2004年高雄醫學大學校友文教基金會優秀論文獎

2004年高雄醫學大學研究傑出教師獎(RPI最佳獎;整合型計畫總主持人獎)

2002年高雄醫學大學生命科學院研究傑出獎

2002年高雄醫學大學教學優良教師

2001年高雄醫學大學生命科學院研究傑出獎

1999年訓育委員會訓輔工作績優人員獎

1997年高雄醫學院優良教師

1991 - 2000年國科會甲等研究獎勵

    代表著作

  1. Chih-Jyun-Tsai,Chin-Chau-Chen,Chih-Wei,Tsai,Ming-Jung Wu* Base-Mediated Cyclization Reaction of 2-(5-Hydroxy-1-pentynyl)benzonitriles To 4-Amino-2,3-dihydronaphtho[2,3-b]furanes and Synthesis of Furanonaphthoquinones 
    “J. Org. Chem 2016,81卷,9期,3882-3889”

  2. Hung-Chou Wu,Jean-Ho Chu*,Chin-Wei Li,Long-Chih Hwang, Ming-Jung Wu* Palladium-Catalyzed Regioselective Arylation of Pyrazolo[1,5-α]pyridines via C-H Activation and Synthetic Applications on P38 Kinase Inhibitors 
    “Organometallics 2016,35卷02期,288-300”

  3. CLi-Lan Wei,Li-Mei Wei,Po-Yang Lin,Chin-Chau Chen, Wen-Bin Pan*,Ming-Jung Wu* Palladium(0)-catalyzed 5-exo-dig O-cyclization/coupling of ethyl 3-(2-alkynylphenyl)-3-oxopropanoates with aryl iodides to 1,3-dihydroisobenzofurans 
    “Tetrahedron Lett 2015,56卷,47期,6629-6632”

  4. Jean-ho Chu,Shih-Tien Chen,Meng-Fan Chiang,and Ming-Jung Wu* Palladium-Catalyzed Direct Ortho Aroylation of 2-Phenoxypyridines with Aldehydes and Catalytic Mechanism Investigation 
    “Organometallics 2015,34卷05期,953-966”

  5. Chin-Chau Chen,Chu-Mei Chen, and Ming-Jung Wu* Transition Metal-Catalyzed Cascade Cyclization of Aryldiynes to Halogented Benzo[b]naphtho[2,1-d]thiophene Derivatives 
    “J. Org. Chem 2014,79卷10期,4704-4711”

  6. Jean-Ho Chu,Hao-Ping Huang,Wen-Ting Hsu,Shih-Tien Chen and Ming-Jung Wu* Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via C-H Activation/C-C Coupling and Synthetic Applications 
    “Organometallics 2014,33卷05期,1190-1204” 

  7. Jean-Ho Chu*, Wen-Ting Hsu, Yi-Hua Wu, Meng-Fan Chiang, Nan-Hai Hsu, Hao-Ping Huang, and Ming-Jung Wu* Substituent Electronic Effects Direct Intramolecular C-N Cyclization of N-(Biphenyl)pyridine-2-amines Induced by Hypervalent Iodine(III) Reagents 
    “J. Org. Chem 2014,79卷23期,11395-11408”

  8. Chuang DW, Mohamed ES, Chen CC, Chung YM, Brave BD, Wu MJ, Chang FR, Wu YC* Synthesis of 1,5-diphenylpent-3-en-1-yne derivatives utilizing an aqueous B-alkyl Suzuki cross coupling reaction. 
    “Tetrahedron Lett 2013,54卷,38期,5162-5166”

  9. Cheng-Han Lin, Chin-Chau Chen, and Ming-Jung Wu* Mercury(II)-Catalyzed Cyclization of 2-Alkynylphenyl Alkyl Sulfoxides Provides 3-Acylbenzo[b]thiophenes 
    .”Chem.Eur. J. 2013,19卷08期,2578-2581”

  10. Yu-Hsiang Lo , Ying-Ting Lin , Yu-Peng Liu , Tsai-Hui Duh , Pei-Jung Lu, Ming-Jung Wu* Design, synthesis, biological evaluation and molecular modeling studies of 1-aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)- hexen-1,5-diynes as a new class of potent antitumor agents 
    “Eur. J Med Chem 2013,62卷,526-533” 

  11. Jean-Ho Chu, Chung-Chiu Wu, Deng-Hsiang Chang, Ya-Ming Lee, and Ming-Jung Wu* Direct Ortho Arylation of 9 (Pyridin-2-yl)9H carbazoles Bearing a Removable Directing Group via Palladium(II)-Catalyzed C?H Bond Activation 
    “Organometallics 2013,32卷01期,272-282” 

  12. Wen-Bin Pan, Chin-Chau Chen, Li-Lan Wei, Li-Mei Wei, Ming-Jung Wu* One-pot synthesis of 2,20-bisbenzofurans using cuprous chloride as a catalyst 
    “Tetrahedron Lett 2013,54卷21期,2655-2657” 

  13. Hung-Chou Wu, Chia-Wen Yang, Long-Chih Hwang and Ming-Jung Wu* Au(I)-catalyzed and iodine-mediated cyclization of enynylpyrazoles to provide pyrazolo[1,5-a]pyridines 
    “Org. Biomol. Chem. 2012,10卷33期,6640-6648” 

  14. Jean-Ho Chu,Pi-Shan Lin,Ya-Ming Lee,Wei-Ting Shen,Ming-Jung Wu* ”Palladium(II)-Catalyzed One-Pot Syntheses of 9-(Pyridin-2-yl)-9H-carbazoles through a Tandem C-H Activation/C-X(X=C or N)Formation Process”. 
    “Chem. Eur. J 2011,17卷48期,13613-13620” 

  15. Chin-Chau Chen, Shyh-Chyun Yang, Ming-Jung Wu* ”Iodine-Mediated Cascade Cyclization of Enediynes to Iodinated Benzo[a]carbazoles”. 
    “J. Org. Chem 2011,76卷24期,10269-10274” 

  16. H. C. Wu, L. C. Hwang, M. J. Wu,* “Copper-Mediated Cyclization Reaction of Enediynones with Hydrazine Provides Pyrazolo[1,5-a]pyridines” 
    “Org. Biomol. Chem. 2011, 9卷03期, 670-672” 

  17. C. C. Chen, L. Y. Chin, S. C. Yang, M. J. Wu,* “Synthetic Development and Mechanistic Study on Pd(II)-Catalyzed Cyclization of Enediynes to Benzo[a]carbazoles” 
    “Org. Lett. 2010, 12卷24期, 5652.-5655” 

  18. J. H. Chu, P. S. Lin, M. J. Wu,* “Palladium(II)-Catalyzed Ortho Arylation of 2-Phenoxypyridines with Potassium Aryltrifluoroborates via C-H Functionalization” 
    “Organometallics 2010, 29卷18期, 4058-4065” 

  19. C. W. Tsai, S. C. Yang, Y. M. Liu, M. J. Wu* “Microwave-assisted Cycloaddition of 2-Alkynylbenzonitriles with Sodium Azides: Selective Synthesis of Tetrazolo[5,1-a]pyridines and 4,5-Disubstituted-2H-1,2,3-triazoles” 
    “Tetrahedron 2009, 65, 8367-8372” 

  20. J. H. Chu, S. L. Tsai, M. J. Wu* “Palladium(II)-Catalyzed ortho Arylation of 2-Phenylpyridines with Potasium Aryltrifluoroborates by C-H Functionalization” 
    “Synthesis 2009, 3757-3764.” 

  21. J. H. Chu, Y. J. Chen, M. J. Wu* “Mild Oxidation of Diarylacetylenes to 1,2-Diketones Using Oxone in Trifluoroacetic acid” 
    “Synthesis, 2009, 2155-2162.” 

  22. C. Y. Kuo,* M. J. Wu “The Synthesis of N-Phenoxyethyl-1-substituted-1,2,3,4-tetrahydroisoquinolines and Their 1-adrenoceptor Blocking Activity” 
    “Eur. J. Med. Chem. 2009, 44, 1271-1277” 

  23. K. F. Tseng, C. F. Lin, Y. H. Lo, Y. L. Hu, L. Y. Chen, S. H. Yang, S. R. Lin, L. S. Chang, M. J. Wu* “Synthesis and Biological Evalution of Novel Symmetry Bis-enediynes” 
    “Eur. J. Med. Chem. 2009, 44, 35-41.” 

  24. Y. S. Tu, T. H. Duh, C. Y. Tseng, Y. T. Lin, Y. H. Lo, Y. L. Hu, C. H. Chen, C. M. Chien, S. H. Yang, Lin, S. R. S. C. Yang, M. J. Wu* “1-(2-((Z)-6-(2-Trifluoromethylphenyl)hexa-3-en-1,5-diynyl)phenyl)piperidin-2-one as a New Potent Apoptosis Agent” 
    “Bioorg. Med. Chem. 2009, 17, 7412-7417.” 

  25. W. P. Hu, J. J. Liang, C. L. Kao, Y. C. Chen, C. Y. Chen, F. Y. Tsai, M. J. Wu, L. S. Chang, Y. L. Chen, J. J. Wang* “Synthesis and Antitumor Activity of Novel Enediyne-linked Pyrrolo[2,1-c][1,4]benzodiazepine hybrids” 
    “Bioorg. Med. Chem. 2009, 17, 1172-1180.”